Cyclobenzaprine: Generic, Uses, Side Effects, Dosages, Interactions & Warnings

The way it works is not entirely understood but is likely due to central nervous system depression. Using Skelaxin or Flexeril with alcohol can increase the side effects such as dizziness and drowsiness. It can also lead to impaired coordination, which can cause accidents.

• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
• Smooth muscles are the muscles that you don’t have control over, like the muscles in your intestine, stomach and blood vessels.
• If your dose is different, do not change it unless your doctor tells you to do so.
• Do not use it later for another condition unless your doctor directs you to do so.

If so, your healthcare provider may have prescribed a muscle relaxant to help your symptoms. Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms. There is also evidence that cyclical antidepressants may decrease the seizure threshold by interfering with chloride conductance on the GABA receptor. Other side effects not listed may also occur in some patients.

Drug Details

Muscle relaxants are a somewhat common prescription due to the frequency of acute and chronic back pain. Low back pain is a very common issue — it remains among the top five reasons people see a primary healthcare provider. Most cases of low back pain resolve without medical intervention. If other treatments don’t work to alleviate the pain, providers may recommend a muscle relaxant. Providers mainly prescribe antispasmodic skeletal muscle relaxants for musculoskeletal and myofascial pain, especially lower back pain, and muscle spasms.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Flexeril is usually taken once daily for only 2 or 3 weeks. Follow all directions on your prescription label and read all medication guides or instruction sheets. In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward. Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS.

Methocarbamol typically needs to be taken up to 4 times a day, whereas cyclobenzaprine extended-release capsules offer the convenience of once-a-day dosing. Keep in mind that regular cyclobenzaprine tablets may require dosing of up to 3 times a day. Drug interactions may change how your medications work or increase your risk for serious side effects.

Are you currently using Flexeril Tablet?

Another telltale sign of Flexeril addiction is abusing the medication in combination with another substance to produce a greater sense of euphoria. Alcohol is commonly abused alongside muscle relaxers like Flexeril because the substances amplify each others’ effects, causing the individual to experience a more intense sedation or high. Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models.

If you take them together, the side effects are much more intense, which can be dangerous. Yes, prescription muscle relaxers can make you sleepy due to how they affect your central nervous system. Because of this, you should be cautious can flexeril kill a dog about operating heavy machinery, such as driving a car, or making important decisions while taking these medications. However, there is much more clinical research on the effects of cyclobenzaprine for fibromyalgia than tizanidine.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs. Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease.

As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. At oral doses of up to 10 times the human dose, cyclobenzaprine did not adversely affect the reproductive performance or fertility of male or female rats. Cyclobenzaprine did not demonstrate mutagenic activity in the male mouse at dose levels of up to 20 times the human dose. In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks. We dental professionals must be aware of gabapentin’s rise as a drug of abuse, both alone and in combination with other substances. Well, while the dangers of gabapentin to patients may have been somewhat overstated in the media, that doesn’t mean those dangers are not real.

Call your doctor or local poison control center if you think you’ve taken too much of this drug. Call 911 or go to the nearest emergency room immediately if your symptoms are severe. Within the last five years, emergency room department visits related to muscle relaxant abuse almost doubled; they increased from 15,830 to 31,763 visits. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).